What the Data Says

What the Data Says

Review the key studies on ACTIFUSE Bone Graft Substitute in more detail.

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ACTIFUSE Bone Graft Substitute Advantage

ACTIFUSE Bone Graft Substitute Advantage

Understand what distinguishes it from traditional bone graft substitutes.

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Contact Us

Contact a Baxter rep in your area.

Contact a Baxter rep in your area.


How ACTIFUSE Bone Graft Substitute Works

Increased Cell Attachment*1

Accelerated Bone Formation*2

Natural Remodeling*2

ACTIFUSE Bone Graft Substitute is contraindicated where the device is intended as structural/load-bearing support in the skeletal system. ACTIFUSE has not been cleared for use in vertebroplasty.

Attempts should not be made to modify the size of the granules or to change their shape. It is important to maximize contact between existing bone and the implant to ensure proper bone regeneration.

Rx Only. For safe and proper use please refer to full device Instructions for Use for Contraindications, Warnings, and Precautions.

*Preclinical data. Results may not correlate to performance in humans.


  1. Guth, K, Campion C, Buckland T, Hing KA. Effect of silicate-substitution on attachment and early development of human osteoblast-like cells seeded on microporous hydroxyapatite discs. Adv Eng Mater. 2010;12(4):B77-B82.
  2. Hing KA, Wilson LF, Buckland T. Comparative performance of three ceramic bone graft substitutes. Spine J. 2007; 7(4):475-490.